COMPARTMENTS

STYX [ENSP00000346599]

Serine/threonine/tyrosine-interacting protein; Catalytically inactive phosphatase . Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2) . Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2) . By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates . Plays a role in spermatogenesis (By similarity).

Synonyms:  STYX,  A0A024R641,  Q8WUJ0,  Q8WUJ0p,  hQ8WUJ0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM