CDC16 localizations
CDC16 [ENSP00000348554]
Cell division cycle protein 16 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. ; Belongs to the APC6/CDC16 family.
Synonyms: CDC16, CDC16p, hCDC16, A0A024RDZ2, A0A3B3ISD2 ...
Linkouts: STRING Pharos UniProt OMIM
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