COMPARTMENTS

SREBF2 [ENSP00000354476]

Processed sterol regulatory element-binding protein 2; Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'- ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.

Synonyms:  SREBF2,  SREBF2p,  hSREBF2,  A0A024R1Q0,  A0A087X1T2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM