COMPARTMENTS

COMT [ENSP00000354511]

Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

Synonyms:  COMT,  A0A140VJG8,  E7EMS6,  E7EUU8,  F8WBW9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM