COMPARTMENTS

RGS7 [ENSP00000355523]

Regulator of G-protein signaling 7; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form . The RGS7/GNB5 dimer enhances GNAO1 GTPase activity . May play a role in synaptic vesicle exocytosis . Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling .

Synonyms:  RGS7,  RGS7p,  hRGS7,  P49802,  Q5T3H5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM