DEDD localizations
DEDD [ENSP00000356984]
Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity).
Synonyms: DEDD, B1AQP5, O75618, V9GY27, B1AQP5p ...
Linkouts: STRING Pharos UniProt
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