COMPARTMENTS

AS3MT [ENSP00000358896]

Arsenite methyltransferase; Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals . It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2 (PubMed:16407288, PubMed:25997655). Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH .

Synonyms:  AS3MT,  AS3MTp,  hAS3MT,  A0A087WVD4,  Q9HBK9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM