COMPARTMENTS

ROR1 [ENSP00000360120]

Inactive tyrosine-protein kinase transmembrane receptor ROR1; Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo . Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells .

Synonyms:  ROR1,  ROR1p,  hROR1,  A0A0A0MTJ5,  Q01973 ...

Linkouts:  STRING  Pharos  UniProt  OMIM