COMPARTMENTS

PCIF1 [ENSP00000361486]

mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; Cap-specific adenosine methyltransferase that catalyzes formation of N(6),2'-O-dimethyladenosine cap (m6A(m)) by methylating the adenosine at the second transcribed position of capped mRNAs . Recruited to the early elongation complex of RNA polymerase II (RNAPII) via interaction with POLR2A and mediates formation of m6A(m) co- transcriptionally . ECO:0000269|PubMed:30487554, ECO:0000269|PubMed:31279658,

Synonyms:  PCIF1,  PCIF1p,  hPCIF1,  A0A087WWZ2,  Q9H4Z3 ...

Linkouts:  STRING  Pharos  UniProt