SPDEF localizations
SPDEF [ENSP00000363149]
SAM pointed domain-containing Ets transcription factor; May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.
Synonyms: SPDEF, O95238, O95238p, hO95238, 1YO5 ...
Linkouts: STRING Pharos UniProt OMIM
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