ELP1 localizations
ELP1 [ENSP00000363779]
Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation . The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs . Involved in neurogenesis (By similarity). Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha- tubulin acetylation (By similarity). May act as a scaffold protein that may assemble active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK) . ECO:0000269|PubMed:11714725, ECO:0000269|PubMed:11818576,; Belongs to the ELP1/IKA1 family.
Synonyms: ELP1, ELP1p, hELP1, F5H2T0, H0YDF3 ...
Linkouts: STRING Pharos UniProt OMIM
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