HSD17B8 localizations
HSD17B8 [ENSP00000363794]
Estradiol 17-beta-dehydrogenase 8; NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone . The heterotetramer with CBR4 has NADH- dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis . Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD . ; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Synonyms: HSD17B8, HSD17B8p, hHSD17B8, A0A1U9X7U3, Q92506 ...
Linkouts: STRING Pharos UniProt
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