TRIM22 localizations
TRIM22 [ENSP00000369299]
E3 ubiquitin-protein ligase TRIM22; Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22- dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus (EMCV) and hepatitis B virus (HBV). Acts as a transcriptional repressor of HBV core promoter. May have E3 ubiquitin-protein ligase activity.
Synonyms: TRIM22, TRIM22p, hTRIM22, C9J060, C9JIU5 ...
Linkouts: STRING Pharos UniProt OMIM
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