SNCB localizations
SNCB [ENSP00000377296]
Beta-synuclein; Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease; Belongs to the synuclein family.
Synonyms: SNCB, G4Y816, Q16143, G4Y816p, hG4Y816 ...
Linkouts: STRING Pharos UniProt
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