COMPARTMENTS

Subcellular localization database

JensenLab

SLC9B2 localizations

SLC9B2 [ENSP00000378265]

Sodium/hydrogen exchanger 9B2; Na(+)/H(+) antiporter that extrudes Na(+) or Li(+) in exchange for external protons across the membrane (PubMed:18000046, PubMed:28154142, PubMed:22948142, PubMed:18508966). Contributes to the regulation of intracellular pH, sodium homeostasis, and cell volume. Plays an important role for insulin secretion and clathrin-mediated endocytosis in beta-cells (By similarity). Involved in sperm motility and fertility (By similarity). It is controversial whether SLC9B2 plays a role in osteoclast differentiation or not (By similarity). ECO:0000269|PubMed:18508966, ECO:0000269|PubMed:22948142,

Synonyms:  SLC9B2,  SLC9B2p,  hSLC9B2,  A0A024RDJ7,  A0A0C4DGB3 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence