UMOD localizations
UMOD [ENSP00000379438]
Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF . Facilitates neutrophil migration across renal epithelia .
Synonyms: UMOD, I3L1M3, I3L2J2, I3L2K2, I3L3E0 ...
Linkouts: STRING Pharos UniProt
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