KHSRP localizations
KHSRP [ENSP00000381216]
Far upstream element-binding protein 2; Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue- specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs. ECO:0000269|PubMed:11003644, ECO:0000269|PubMed:8940189,
Synonyms: KHSRP, A0A087WTP3, M0QXW7, M0QYG1, M0QYH3 ...
Linkouts: STRING Pharos UniProt OMIM
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