PTPN6 localizations
PTPN6 [ENSP00000391592]
Tyrosine-protein phosphatase non-receptor type 6; Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Synonyms: PTPN6, PTPN6p, hPTPN6, F5GXD4, F5GY79 ...
Linkouts: STRING Pharos UniProt OMIM
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