COMPARTMENTS

DOHH [ENSP00000398882]

Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF- 5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine . Hypusination is unique to mature eIF-5A factor and is essential for its function (By similarity). Rule:MF_03101, ECO:0000269|PubMed:16371467,

Synonyms:  DOHH,  Q9BU89,  Q9BU89p,  hQ9BU89,  1.14.99.29 ...

Linkouts:  STRING  Pharos  UniProt