COMPARTMENTS

EWSR1 [ENSP00000400142]

RNA-binding protein EWS; Might normally function as a transcriptional repressor. EWS- fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes; Belongs to the RRM TET family.

Synonyms:  EWSR1,  EWSR1p,  hEWSR1,  A0A0D9SFL3,  B0QYJ3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM