COMPARTMENTS

PLCL1 [ENSP00000402861]

Inactive phospholipase C-like protein 1; Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol. Component in the phospho- dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.

Synonyms:  PLCL1,  PLCL1p,  hPLCL1,  A0A0A0MT40,  F8WAR2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM