SMYD3 localizations
SMYD3 [ENSP00000419184]
Histone-lysine N-methyltransferase SMYD3; Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation . Also methylates 'Lys-5' of histone H4 . Plays an important role in transcriptional activation as a member of an RNA polymerase complex . Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences ; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family.
Synonyms: SMYD3, SMYD3p, hSMYD3, A8MXR1, B0QZ88 ...
Linkouts: STRING Pharos UniProt
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