COMPARTMENTS

TCEA1 [ENSP00000428426]

Transcription elongation factor A protein 1; Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.

Synonyms:  TCEA1,  TCEA1p,  hTCEA1,  A0A1W2PPV7,  A0A1W2PPZ5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM