COMPARTMENTS

CYP2E1 [ENSP00000440689]

Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) . Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids . May be involved in the oxidative metabolism of xenobiotics (Probable).

Synonyms:  CYP2E1,  CYP2E1p,  hCYP2E1,  F5H694,  H0Y593 ...

Linkouts:  STRING  Pharos  UniProt