COMPARTMENTS

HPR [ENSP00000441828]

Haptoglobin-related protein; Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.

Synonyms:  HPR,  A0A0A0MRD9,  A0A3B3ISM1,  J3KTC3,  P00739 ...

Linkouts:  STRING  Pharos  UniProt