NKRF localizations
NKRF [ENSP00000442308]
NF-kappa-B-repressing factor; Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK- kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
Synonyms: NKRF, A3F769, NRF, O15226, A3F769p ...
Linkouts: STRING Pharos UniProt OMIM
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