PLXNB3 localizations
PLXNB3 [ENSP00000442736]
Plexin-B3; Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA- mediated inactivation of RAC1; Belongs to the plexin family.
Synonyms: PLXNB3, PLXNB3p, hPLXNB3, H7BZV5, H7C0P4 ...
Linkouts: STRING Pharos UniProt OMIM
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