COMPARTMENTS

DND1 [ENSP00000445366]

Dead end protein homolog 1; RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence- specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity).

Synonyms:  DND1,  DND1p,  hDND1,  Q8IYX4,  Q8IYX4p ...

Linkouts:  STRING  Pharos  UniProt