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Subcellular localization database

JensenLab
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ZBTB1 localizations

ZBTB1 [ENSP00000451000]

Zinc finger and BTB domain-containing protein 1; Acts as a transcriptional repressor . Represses cAMP-responsive element (CRE)-mediated transcriptional activation . In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis . Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity). ECO:0000269|PubMed:20797634, ECO:0000269|PubMed:21706167,

Synonyms:  ZBTB1,  ZBTB1p,  hZBTB1,  G3V2I8,  G3V3N0 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence

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The subcellular localizations are derived from database annotations, automatic text mining of the biomedical literature, and sequence-based predictions. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Janos Binder, Sune Frankild, Kalliopi Tsafou, Christian Stolte, Sean O'Donoghue, Reinhard Schneider, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research (CPR), the Luxembourg Centre for Systems Biomedicine (LCSB), and the Commonwealth Scientific and Industrial Research Organisation (CSIRO).

Currently maintained by Qingyao Huang at Swiss Institute of Bioinformatics, University of Zurich. Licensed under CC BY 4.0.