COMPARTMENTS

CIRBP [ENSP00000466025]

Cold-inducible RNA-binding protein; Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'- UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

Synonyms:  CIRBP,  D6W5Y5,  F6WMK9,  K7EIF7,  K7EJV1 ...

Linkouts:  STRING  Pharos  UniProt