COMPARTMENTS

ACLY localizations

ACLY [ENSP00000466259]

ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis. ECO:0000269|PubMed:1371749, ECO:0000269|PubMed:19286649,; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

Synonyms: ACLY, A0A024R1T9, A0A024R1Y2, K7EIE7, K7ESG8 ...

Linkouts: STRING Pharos UniProt

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The subcellular localizations are derived from database annotations, automatic text mining of the biomedical literature, and sequence-based predictions. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Janos Binder, Sune Frankild, Kalliopi Tsafou, Christian Stolte, Sean O'Donoghue, Reinhard Schneider, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research (CPR), the Luxembourg Centre for Systems Biomedicine (LCSB), and the Commonwealth Scientific and Industrial Research Organisation (CSIRO).

Currently maintained by Qingyao Huang at Swiss Institute of Bioinformatics, University of Zurich. Licensed under CC BY 4.0.