COMPARTMENTS

MR1 [ENSP00000477563]

Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T- cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.

Synonyms:  MR1,  MR1p,  hMR1,  Q95460,  Q95460p ...

Linkouts:  STRING  Pharos  UniProt