CBY1 localizations
CBY1 [ENSP00000478962]
Protein chibby homolog 1; Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. ; Belongs to the chibby family.
Synonyms: CBY1, CBY1p, hCBY1, A0A024R1L9, A0A087WUW0 ...
Linkouts: STRING Pharos UniProt
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