THEMIS localizations
THEMIS [ENSP00000487358]
Protein THEMIS; Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. ; Belongs to the themis family.
Synonyms: THEMIS, A0A0D9SFD2, Q8N1K5, X1WI26, Q8N1K5p ...
Linkouts: STRING Pharos UniProt
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