NLRP2B localizations
NLRP2B [ENSP00000488995]
NLR family pyrin domain-containing protein 2B; May function as a negative regulator of NF-kappa-B by preventing RELA/p65 phosphorylation at 'Ser-536', thereby inhibiting its transcriptional activity. Through NF-kappa-B regulation may control cytokine release upon Toll-like receptors activation and therefore play a role in modulation of innate immunity. May also play a role in cell cycle progression and apoptotic process.
Synonyms: NLRP2B, NLRP2Bp, hNLRP2B, P0DMW2, P0DMW2p ...
Linkouts: STRING Pharos UniProt
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