LZTR1 localizations
LZTR1 [ENSP00000496779]
Leucine-zipper-like transcriptional regulator 1; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS) (PubMed:30442762, PubMed:30442766, PubMed:30481304). Is a negative regulator of RAS-MAPK signaling that acts by controlling Ras levels and decreasing Ras association with membranes (PubMed:30442762, PubMed:30442766, PubMed:30481304); Belongs to the LZTR1 family.
Synonyms: LZTR1, LZTR1p, hLZTR1, A0A2R8Y4K9, A0A2R8Y656 ...
Linkouts: STRING Pharos UniProt
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