COMPARTMENTS

LDB1 [ENSP00000501277]

LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity). ; Belongs to the LDB family.

Synonyms:  LDB1,  LDB1p,  hLDB1,  Q86U70,  Q86U70p ...

Linkouts:  STRING  Pharos  UniProt